Bridging the Gap Between Transformative Practices and Traditional Public Health Approaches.

CONTEXT: The release of the 24/7 Wall Street publication in November 2018 labeling the Waterloo-Cedar Falls, Iowa, community as the worst city for Black Americans to live in the United States sparked conversations and calls to action across the community-from the kitchen table to the boardroom. It became clear that this was a critical moment for innovative leadership from public health. PROGRAM: To bring together these individual efforts, and diverse perspectives, toward deeper understanding and system transformation, Black Hawk County Public Health, with support from Engaging Inquiry, adopted a participatory action approach of dynamic system mapping and systemic strategy design. IMPLEMENTATION: Using participatory methodologies and tools for systems analysis, stakeholders developed a system map visualizing the patterns driving inequitable outcomes, but also the bright spots and resiliencies, identified and experienced across the community. This map, populated with local stories and data, represents a "theory of context," and offered a foundation of understanding and connectivity upon which high-impact opportunities for engagement could be identified and developed. By working across sectors and building on existing energy and resources present within the community, systemic strategies were designed to foster critical shifts toward a healthier community. EVALUATION: A developmental evaluation approach is applied throughout the mapping process to maximize rapid learning and adaption of a complex challenge when stakeholder engagement and trust building is essential. DISCUSSION: Participatory systems mapping shows promise as an adaptive approach to allow public health departments to go beyond the traditional roles of public health practice, to collaborate with nontraditional partners, and implement strategies, initiatives, and/or policies that explicitly address inequity and the social determinants of health. Adaptive strategies provide opportunities for the local public health system to identify community health improvement strategies that align with Public Health 3.0.

Word cloud analysis of historical changes in the subject matter of public health practice in the United Kingdom.

OBJECTIVES: This study aimed to use the content of the journal Public Health to paint a picture of changing public health practice in the United Kingdom over the last 150 years. STUDY DESIGN: Word cloud analysis was used in this study. METHODS: Word clouds were generated for all issues in three separate years, 65 years apart, chosen to represent entirely different periods of public health practice - 1888, 1953 and 2018. RESULTS: The analysis has been successful in illustrating how the focus of public health practice has changed over the last 150 years in the United Kingdom. CONCLUSION: The majority of the analysis has corresponded with the four waves of public health improvement as set out by Hanlon et al. moving from the response to infectious disease caused by the problems of the Industrial Revolution to a focus on the determinants of health and well-being that lie behind chronic diseases, such as cancer. The most recent word cloud for 2018 has illustrated the holistic nature of modern public health practice, the multidisciplinary nature of its workforce and the fact that it is much more gender balanced than in the past.

Yoga: um diálogo com a Saúde Coletiva / Yoga: un diálogo con la Salud Colectiva / Yoga: dialoguing with Collective Health

A tradição indiana milenar do yoga oportuniza o autoconhecimento dos indivíduos em suas possibilidades e limitações, tornando-os mais autônomos na busca de bem-estar, mais saudáveis e conscientes. O ensaio teórico, fundamentado na revisão da literatura, analisa a repercussão do yoga em algumas de suas implicações como prática de saúde na racionalidade ocidental. A apropriação do yoga pela cultura ocídua implica a compreensão do sistema capitalista sobre o modo de produzir saúde nas sociedades contemporâneas e no aprofundamento das discussões acerca de seus benefícios filosóficos e práticos na Saúde Coletiva. Esse aprendizado fundamenta o Sistema Único de Saúde (SUS) e vem consolidando o conceito ampliado de saúde por meio da criação de pontes culturais baseadas na tolerância e no respeito a sua tradição. (AU)

La tradición hindú milenaria del yoga da oportunidad al autoconocimiento de los individuos en sus posibilidades y limitaciones, haciéndolos más autónomos en la búsqueda de bienestar, más saludables y conscientes. El ensayo teórico, fundamentado en la revisión de la literatura, analiza la repercusión del yoga en algunas de sus implicaciones como práctica de salud en la racionalidad occidental. La apropiación del yoga por la cultura occidua implica la comprensión del sistema capitalista sobre el modo de producir salud en las sociedades contemporáneas y la profundización de las discusiones sobre sus beneficios filosóficos y prácticos en la salud colectiva. Ese aprendizaje fundamenta el Sistema Brasileño de Salud (SUS) y consolida el concepto ampliado de salud, a partir de la creación de puentes culturales basados en la tolerancia y respeto a su tradición. (AU)

The ancient tradition of yoga coming from India provides individuals with self-knowledge regarding their possibilities and limitations, making them more autonomous in the search for well-being, healthier and more conscious. This theoretical essay, based on the literature review, analyzes the repercussion of yoga through some of its implications as a health practice within Western rationality. The appropriation of yoga by the Western culture implies an understanding of the capitalist system regarding the way of producing health in contemporary societies, and in the deepening of discussions about its philosophical and practical benefits in public health. This construction underlies the Brazilian National Health Sytem (SUS), and helped in the consolidation of an expanded concept of health, creating cultural bridges based on tolerance and respect for its tradition. (AU)

Community approaches to epidemic management in South Sudan. Lessons from local healthcare systems in tackling COVID-19

Across South Sudan, long before the global COVID-19 pandemic emerged, communities have created systems and structures to control the spread of epidemics and infectious diseases. South Sudanese people have extensive knowledge of infectious diseases and experience of organizing responses to epidemics during wars and other crises. Most people have experience of multiple epidemics within their households and neighbourhoods. Many informal healthcare providers have been involved directly in organized medical responses to past epidemic outbreaks: in several areas of the country people have been involved in contact tracing and infection management since the 1970s. This research report details community infectious disease management strategies developed within the realities of South Sudan's local healthcare systems. Because the South Sudan clinical healthcare sector is overstretched and only semi-functional, the majority of South Sudanese people mostly rely on non-clinical medical advice and support from a wide field of healthcare workers and caregivers, including small private clinics and unlicenced pharmaceutical sellers, traditional herbal and surgical experts, midwives and spiritual healers. South Sudanese community-led infectious disease management relies on symptomatic identification, the containment of potential infections through applying knowledge of infection vectors and pathologies, and creative treatment using a high level of botanical knowledge. There are multiple, locally-specific methods used by communities for interrupting infection transmission and managing epidemics. For airborne diseases or infections spread through contact, people often organize houses for self-isolation, mark out separate food and water access points for households, make homemade rehydration salts, carefully manage dirty linen, bed spaces and drinking water provision to avoid cross-contamination, and use urine, hot water and ashes for disinfecting. Different communities across the country use crossed posts, rope barriers, or ash markings across paths to warn people away from sick households in quarantine. Particular care is taken to avoid transmission to high-risk residents, especially pregnant and post-partum women and young children. Across research sites, people are already working on developing local safety measures and strategies to prevent the further spread of COVID-19 in South Sudan. This research documents these community infectious disease management strategies, based on sustained investigative research in the Yei, Juba, Wau, Malakal, Aweil West and Rubkona areas, both in-person and remotely via telephone, from August to November 2020.1 The health and wellbeing of the team and our interviewees was the prioritythroughout the project. Interviewees include midwives and traditional birth attendants, male and female nurses, herbal experts, traditional healers, pharmacists, chiefs and community elders, elderly women, and local public health workers, among many others. Recommendations for action include: 1. Collaborate with wider non-clinical health workers and caregivers, who are often first responders, including women, midwives, herbal experts and local pharmaceutical sellers. Include these workers in public health planning and clinical training. 2. Support communities with the broad epidemiological and logistical skills to prepare for COVID-19 and other epidemic outbreaks. Build sustained and detailed public health information systems to help local non-clinical and clinical workers plan locally appropriate infectious disease management strategies. More detailed and sustained information drives, in partnership with local first responders, will also build trust and counter misinformation and fatigue. 3. Localise epidemic response planning. Central planning is heavy handed and ineffective, overlooking critical local knowledge and community leadership that will make responses effective. Public health strategies should aim to build on measures people already take to try to protect themselves and their communities from multiple infectious diseases.

Vitamin D Insufficiency and Deficiency in the Eastern Mediterranean Region (EMR)-Misconceptions in Public Health Practice: A Scoping Review 2019-2020.

Vitamin D insufficiency and deficiency are a growing concern in the reasonably sunny Eastern Mediterranean Region (EMR). Variances in the metabolism of vitamin D across populations were observed and several biological and environmental factors are reported to affect its pathways and regulatory mechanisms. Methodologies for the assessment of vitamin D indicator metabolite and threshold levels for inadequacy remain evidently controversial. This review was conducted to appraise how vitamin D status is evaluated in populations of EMR. Online databases including PubMed and Google Scholar, and websites of UN agencies and ministries of health were searched thoroughly. Surveys and cross-sectional studies conducted between 2009 and 2019 which are reporting vitamin D levels in countries of EMR were retrieved and included in this review. Surveys from Afghanistan, Iran, Iraq, Jordan, Kuwait, Oman, Pakistan, and Saudi Arabia, were included in this review. The indicator mostly reported for vitamin D status assessment was 25-hydroxyvitamin D in serum samples. Differences between countries in the cut-off levels used for assessment of vitamin D status were observed. Mostly the surveys adopted either the Institute of Medicine (IOM) or the Endocrine Society (ES) guidance, but even those showed overlap in defining insufficiency and deficiency. This discordance in cut-offs jeopardizes the credibility of results and regional and global comparability. We concluded that there is a lack of consensus on the methodologies used to assess vitamin D levels across EMR. There is an urgent need for guidance on clinical and public health practices on the assessment of vitamin D status.

Child safety, protection, and safeguarding in the time of COVID-19 in Great Britain: Proposing a conceptual framework.

BACKGROUND: Great Britain has the highest coronavirus death rate in Europe. While the pandemic clearly poses a risk to the lives and wellbeing of vulnerable groups, necessary public health measures taken to delay or limit the spread of the virus have led to distinctive challenges for prevention, family support, court processes, placement and alternative care. The pandemic has also come about at a time when statutory changes to partnerships have led to a reduction in the importance of educational professional representation in the new formulation in England and Wales. OBJECTIVES: In this discussion paper, we propose a novel and pragmatic conceptual framework during this challenging time. PARTICIPANTS: We consulted with 8 education professionals and 4 field-based student social workers. SETTING: Bodies responsible for safeguarding have been working quickly to develop new approaches to fulfilling their responsibilities, for example through online home visits and case conferences. However, some communities have been highlighted as experiencing particular challenges because of the pandemic and its impacts. Protection of vulnerable children is increasingly dependent on individualised - and often pathologising - practice with a lack of emphasis on the importance of the social. Holistic consideration of the child is side-lined. RESULTS: Our framework comprises two phases: pandemic and aspirational. CONCLUSION: The framework illuminates the importance of interconnected sectors and multi-agency working, the need for resilient and adaptable support systems, and the need to promote the importance of children's rights and voices to be heard above the noise of the pandemic.

The Yin and the Yang of Treatment for Chronic Hepatitis B-When to Start, When to Stop Nucleos(t)ide Analogue Therapy.

Over 257 million individuals worldwide are chronically infected with the Hepatitis B Virus (HBV). Nucleos(t)ide analogues (NAs) are the first-line treatment option for most patients. Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) are both potent, safe antiviral agents, have a high barrier to resistance, and are now off patent. They effectively suppress HBV replication to reduce the risk of cirrhosis, liver failure, and hepatocellular carcinoma (HCC). Treatment is continued long-term in most patients, as NA therapy rarely induces HBsAg loss or functional cure. Two diverging paradigms in the treatment of chronic hepatitis B have recently emerged. First, the public health focussed "treat-all" strategy, advocating for early and lifelong antiviral therapy to minimise the risk of HCC as well as the risk of HBV transmission. In LMICs, this strategy may be cost saving compared to monitoring off treatment. Second, the concept of "stopping" NA therapy in patients with HBeAg-negative disease after long-term viral suppression, a personalised treatment strategy aiming for long-term immune control and even HBsAg loss off treatment. In this manuscript, we will briefly review the current standard of care approach to the management of hepatitis B, before discussing emerging evidence to support both the "treat-all" strategy, as well as the "stop" strategy, and how they may both have a role in the management of patients with chronic hepatitis B.

Lessons from the Field: Lessons from Yap - Changing Government and Cultural Practice Through Public Health Policy.

The heavy burden of non-communicable diseases (NCD) in Yap State, Federated States of Micronesia overwhelms the resources of this small population. Traditional cultural practices strongly influence all aspects of life, especially in the remote outer islands. The traditional Chiefs must grant permission to perform any type of health outreach or services for about one-third of the population. One key cultural practice promotes tobacco and alcohol use. The Yap Comprehensive Cancer Control Program, in collaboration with other entities in public health, systematically engaged the traditional Chiefs, resulting in a landmark policy that paved the way for other system and environmental interventions to reduce the risks of developing NCD.

Addressing Health Equity in Public Health Practice: Frameworks, Promising Strategies, and Measurement Considerations.

This review describes the context of health equity and options for integrating equity into public health practice. We first discuss how the conceptualization of health equity and how equity considerations in US public health practice have been shaped by multidisciplinary engagements. We then discuss specific ways to address equity in core public health functions, provide examples of relevant frameworks and promising strategies, and discuss conceptual and measurement issues relevant to assessing progress in moving toward health equity. Challenges and opportunities and their implications for future directions are identified.

The 2017 Oslo conference report on neglected tropical diseases and emerging/re-emerging infectious diseases - focus on populations underserved.

BACKGROUND: In 2017, the Centre for Global Health (CGH) at the University of Oslo in collaboration with the Coalition for Epidemic Preparedness Innovations (CEPI) and the Norwegian Agency for Development Cooperation (Norad) held a meeting to discuss together with leading figures in disease control, research and development the issue of neglected tropical diseases and emerging/re-emerging infectious diseases. This commentary has taken up this discussion and the conclusions drawn at this meeting to make a case for the opportunity the Sustainable Development Goals (SDGs) provide in highlighting the interconnectedness of factors that are relevant in the successful fight against neglected tropical diseases (NTDs) and emerging infectious diseases (EIDS). MAIN BODY: Despite NTDs being endemic and EIDS being epidemic, in order to prevent both disease groups effectively, it is important to appreciate that they share essential health determining factors, namely: neglect, poverty, a lack of access to clean water and sanitation facilities and an absence of or severely limited provision of healthcare as well as in many cases a zoonotic nature. Instead of looking to "simple disease management" for the answer, the SDGs help to understand the interplay of multiple priority areas and thereby help to promote a more holistic approach to addressing these two disease groups. CONCLUSIONS: Their commonalities mean that the Global Health community should leverage opportunities and efforts in the prevention and elimination of both NTDs and EIDs. Doing so using a One Health approach is considered to offer a "public health best-buy". Concrete solutions are proposed.

Real-World Evidence of Patient Outcome Following Treatment of Advanced Gastrointestinal Stromal Tumor (GIST) with Imatinib, Sunitinib, and Sorafenib in Publicly Funded Health Care in Poland.

BACKGROUND This study aimed to undertake an analysis of ten years of real-world evidence (RWE) on overall survival (OS) following treatment of advanced gastrointestinal stromal tumor (GIST) with imatinib, sunitinib, and sorafenib using data from the Polish National Health Fund. MATERIAL AND METHODS Data from the Polish National Health Fund, the sole Polish public payer, identified 1,641 patients with advanced GIST who were treated with imatinib (n=1047), sunitinib (n=457), and sorafenib (n=137). The differences in overall survival (OS) were analyzed. RESULTS For patients with advanced GIST, the median follow-up time for patients treated with imatinib was 71 months (95% CI, 64.8-79.2), the median OS was 56.9 months (95% CI, 50.4-61.2), with survival at 12 months (89.5%), 24 months (77.9%), 36 months (66.9%), and 60 months (48.4%). The median follow-up time for patients treated with sunitinib was 41.4 months (95% CI, 34.6-49.3), the median OS was 22.8 months (95% CI, 19.2-26.8), with survival at 12 months (68.2%), 24 months (47.1%), and 36 months (31%). The median follow-up time for patients treated with sorafenib was 17.4 months (95% CI, 14.6-22.9), the median OS was 16.9 months (95% CI, 13.7-24.3), with survival at 12 months (61.9%), at 24 months (36.2%), and at 36 months (16.8%). CONCLUSIONS Real-world data collected in a ten-year period confirmed the effectiveness of the use of imatinib, sunitinib, or sorafenib for the treatment of advanced GIST and was comparable with the findings from clinical trials.

Keeping our immigrants healthy: hygienist doctrine in the Hospedaria de Imigrantes da Ilha das Flores. / Como manter saudáveis nossos imigrantes: preceitos higienistas na constituição da Hospedaria de Imigrantes da Ilha das Flores.

The Hospedaria de Imigrantes (Immigrant Lodgings) da Ilha das Flores was established in 1883 in accordance with the hygienist thinking of the time. Immigrants were isolated on the east coast of Guanabara Bay because of the epidemics of yellow fever which returned to the Imperial capital every summer since 1849-1850. Hygienists attributed the disease to the precarious health conditions in the city of Rio de Janeiro, which enabled germs to multiply and infect the atmosphere. As physicians reinterpreted the disease in light of Pasteurian theory, new procedures were adopted to receive immigrants, changing the structure and function of the facility on Ilha das Flores.

A criação da Hospedaria de Imigrantes da Ilha das Flores, em 1883, esteve de acordo com os preceitos higienistas vigentes na época. O isolamento de imigrantes na costa leste da baía de Guanabara ocorreu em virtude das epidemias de febre amarela que retornavam à capital do Império todo verão, desde 1849-1850. Higienistas atribuíam a doença à precária condição sanitária da cidade do Rio de Janeiro, que propiciava a multiplicação do germe e infeccionava a atmosfera. Na medida em que os médicos reinterpretavam a doença à luz da teoria pasteuriana, foram sendo adotados novos procedimentos para a recepção de imigrantes, alterando a estrutura e o funcionamento da Hospedaria da Ilha das Flores.

A comparative ethnography of nutrition interventions: Structural violence and the industrialisation of agrifood systems in the Caribbean and the Pacific.

Public health interventions that involve strategies to re-localise food fail in part because they pay insufficient attention to the global history of industrial food and agriculture. In this paper we use the method of comparative ethnography and the concept of structural violence to illustrate how historical and geographical patterns related to colonialism and industrialisation (e.g. agrarian change, power relations and trade dependencies) hinder efforts to address diet-related non-communicable diseases on two small islands. We find comparative ethnography provides a useful framework for cross-country analysis of public health programmes that can complement quantitative analysis. At the same time, the concept of structural violence enables us to make sense of qualitative material and link the failure of such programmes to wider historical and geographical processes. We use ethnographic research carried out from April to August 2013 and from June to July 2014 in Trinidad (with follow-up online interviews in 2018) and in Nauru from February to May 2010 and August 2010 to February 2011. Our island case studies share commonalities that point to similar experiences of colonialism and industrialisation and comparable health-related challenges faced in everyday life.

Como manter saudáveis nossos imigrantes: preceitos higienistas na constituição da Hospedaria de Imigrantes da Ilha das Flores / Keeping our immigrants healthy: hygienist doctrine in the Hospedaria de Imigrantes da Ilha das Flores

Resumo A criação da Hospedaria de Imigrantes da Ilha das Flores, em 1883, esteve de acordo com os preceitos higienistas vigentes na época. O isolamento de imigrantes na costa leste da baía de Guanabara ocorreu em virtude das epidemias de febre amarela que retornavam à capital do Império todo verão, desde 1849-1850. Higienistas atribuíam a doença à precária condição sanitária da cidade do Rio de Janeiro, que propiciava a multiplicação do germe e infeccionava a atmosfera. Na medida em que os médicos reinterpretavam a doença à luz da teoria pasteuriana, foram sendo adotados novos procedimentos para a recepção de imigrantes, alterando a estrutura e o funcionamento da Hospedaria da Ilha das Flores.

Abstract The Hospedaria de Imigrantes (Immigrant Lodgings) da Ilha das Flores was established in 1883 in accordance with the hygienist thinking of the time. Immigrants were isolated on the east coast of Guanabara Bay because of the epidemics of yellow fever which returned to the Imperial capital every summer since 1849-1850. Hygienists attributed the disease to the precarious health conditions in the city of Rio de Janeiro, which enabled germs to multiply and infect the atmosphere. As physicians reinterpreted the disease in light of Pasteurian theory, new procedures were adopted to receive immigrants, changing the structure and function of the facility on Ilha das Flores.

Prioritizing Population Approaches in Cancer Prevention and Control: Results of a Case Study Evaluation of Policy, Systems, and Environmental Change.

Development and implementation of policy, systems, and environmental (PSE) change is a commonly used public health approach to reduce disease burden. The Centers for Disease Control and Prevention's National Comprehensive Cancer Control Program conducted a demonstration with 13 programs to determine whether and to what extent dedicated resources would enhance the adoption of PSE strategies. This paper describes results of the qualitative portion of a longitudinal, mixed-methods evaluation of this demonstration. Case studies were conducted with a diverse subset of the 13 programs, and 106 in-depth interviews were completed with state/tribal program staff, community partners, and decision makers. Interviews addressed PSE change planning and capacity building, partnerships, local context, and how programs achieved PSE change. Dedicated PSE resources, including a policy analyst, helped increase PSE change capacity, intensify focus on PSE change overall, and accomplish specific PSE changes within individual jurisdictions. Stakeholders described PSE change as a gradual process requiring preparation and prioritization, strategic collaboration, and navigation of local context. Findings suggest that the demonstration program, including PSE-dedicated funds and a policy analyst, was successful in both increasing PSE change capacity and achieving PSE change itself. These results may be useful to other state, tribal, territorial, and public health organizations planning or implementing PSE change strategies.

Maternal and child characteristics and health practices affecting under-five mortality: A matched case control study in Gamo Gofa Zone, Southern Ethiopia.

BACKGROUND: Though Ethiopia has shown a considerable improvement in reducing under-five mortality rate since 1990, many children still continue to die prematurely. Mixed results have been reported about determinants of under-five mortality. Besides, there is paucity of mortality studies in the current study site. Therefore, this study was conducted to assess maternal and child health related predictors of under-five mortality in Southern Ethiopia. METHODS: A matched case control study was conducted in 2014 in Arba Minch Town and Arba Minch Zuria District of Gamo Gofa Zone, Southern Ethiopia. Conditional logistic regression was employed to identify the predictors of under-five mortality. Sampling weight was applied to account for the non-proportional allocation of sample to different clusters. Based on the Mosley & Chen's analytical framework for under-five and infant mortalities, the predictors were organized in to three groups: 1) personal illness control, 2) child feeding and newborn care and 3) other maternal and child related factors. RESULTS: Among personal illness control related factors: lack of post-natal care, immunization status of the child and lack of Vitamin A supplementation were significantly associated with higher rate of under-five mortality. Not breastfeeding and delaying first bath at least for 24 hours were child feeding and newborn care related factors which were found to be significantly associated with under-five mortality. Among other maternal and child related factors, shorter previous birth interval, history of death of index child's older sibling, being multiple birth and live birth after the index child were significantly associated with under-five mortality. CONCLUSIONS: In order to maintain reduction of under-five mortality during the Sustainable Development Goals era, strengthening of maternal and child health interventions, such as post-natal care, family planning, immunization, supplementation of Vitamin A for children older than six months, breastfeeding and delaying of first bath after delivery at least for 24 hours are recommended.

Trauma system in Greece: Quo Vadis?

INTRODUCTION: Implementation of trauma systems has markedly assisted in improving outcomes of the injured patient. However, differences exist internationally as diverse social factors, economic conditions and national particularities are placing obstacles. The purpose of this paper is to critically evaluate the current Greek trauma system, provide a comprehensive review and suggest key actions. METHODS: An exhaustive search of the - scarce on this subject - English and Greek literature was carried out to analyze all the main components of the Greek trauma system, according to American College of Surgeons' criteria, as well as the WHO Trauma Systems Maturity Index. RESULTS: Regarding prevention, efforts are in the right direction lowering the road traffic incidents-related death rate, however rural and insular regions remain behind. Hellenic Emergency Medical Service (EKAB) has well-defined communications and emergency phone line but faces problems with educating people on how to use it properly. In addition, equal and systematic training of ambulance personnel is a challenge, with the lack of pre-hospital registry and EMS quality assessment posing a question on where the related services are currently standing. Redistribution of facilities' roles with the establishment of the first formal trauma centre in the existing infrastructure would facilitate the development of a national registry and introduction of the trauma surgeon subspecialty with proper training potential. Definite rehabilitation institutional protocols that include both inpatient and outpatient care are needed. Disaster preparedness entails an extensive national plan and regular drills, mainly at the pre-hospital level. The lack, however, of any accompanying quality assurance programs hampers the effort to yield the desirable results. CONCLUSION: Despite recent economic crisis in Greece, actions solving logistics and organising issues may offer a well-defined, integrated trauma system without uncontrollably raising the costs. Political will is needed for reforms that use pre-existing infrastructure and working power in a more efficient way, with a first line priority being the establishment of the first major trauma centre that could function as the cornerstone for the building of the Greek trauma system.

A qualitative exploration of stakeholder perceptions of the implementation of place-based working and its potential to reduce health inequality.

Background: Local authorities (LAs) have statutory responsibility to reduce health inequalities and improve public health. Place-based approaches may positively influence service provision yet little is known about their implementation and potential for reducing inequality through health and wellbeing improvements. An English LA implemented a place-based working (PBW) pilot in a small geography during austerity measures in the north of England. This involved three strands (early intervention, estate services and community intelligence) which were introduced separately and covered overlapping geographies. Predominantly focusing on early intervention, this qualitative study investigates stakeholders' perceptions of the pilot and its potential to improve health and wellbeing by reducing inequality. Methods: In total, 15 face-to-face qualitative interviews with stakeholders were completed. Thematic analysis produced context, mechanism and outcome configurations in a process adapted from realist evaluation methodology. Results: Stakeholders described PBW as holistic, upstream and cutting across departmental boundaries to engage staff and the community. Collaborative working was considered important and was aided by PBW in our study. Conclusions: PBW has the potential to reduce health inequalities by improving health and wellbeing. LAs deliver services that affect health and wellbeing and PBW may help develop a more coordinated response to improve outcomes and potentially save money.